Peptide-Based Drug Design: Methods and Protocols (Methods in Molecular Biology 494)
By addebook • Sep 8th, 2008 • Category: Pharmacy •
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Peptide-Based Drug Design: Methods and Protocols (Methods in Molecular Biology 494)
Peptide-Based Drug Design: Methods and Protocols (Methods in Molecular Biology)
By Laszlo Otvos
Publisher: Humana Press
Number Of Pages: 304
Publication Date: 2008-09-12
ISBN-10 / ASIN: 1588299902
ISBN-13 / EAN: 9781588299901
Binding: Hardcover
Due to their high specificity and low toxicity profile, peptides have once again become central to the development of new drugs. In Peptide-Based Drug Design: Methods and Protocols, expert researchers provide a handbook which offers a selection of research and production tools suitable for transforming a promising protein fragment or stand-alone native peptide into a pharmaceutically acceptable composition. The volume delves into contemporary, cutting-edge subjects such as hit isolation and target validation, computer-aided design, sequence modifications to satisfy pharmacologists, in vivo stability and imaging, and the actual production of difficult sequences. Written in the highly successful Methods in Molecular Biology™ series format, chapters include readily reproducible, step-by-step laboratory protocols, lists of materials, and the Notes section, which highlights tips on troubleshooting and avoiding known pitfalls.
Comprehensive and up-to-date, Peptide-Based Drug Design: Methods and Protocols shows its subject to be an independent science on the rise, and provides scientists with a clear, concise guide for continuing this vital research.
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