Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity
By addebook • Aug 26th, 2008 • Category: BiologyMolecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity

Molecular and Cellular Aspects of the Serpinopathies and Disorders in Serpin Activity
By Gary A. Silverman, David A. Lomas
Publisher: World Scientific Publishing Company
Number Of Pages: 672
Publication Date: 2007-02-27
ISBN-10 / ASIN: 9812569634
ISBN-13 / EAN: 9789812569639
Binding: Hardcover
Massive thrombosis or bleeding, hereditary angioedema, Alzheimer’s disease, diabetic angiopathy and tumor invasion are some of the human diseases associated with serpins. In addition, mutations that alter serpin conformations (the serpinopathies) lead to lung disease, cirrhosis and a form of familial dementia. The goal of this text is to present the current knowledge on the molecular and cellular basis of serpins and their diseases.
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