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Mitochondria: Practical Protocols (Methods in Molecular Biology)

By addebook • Jun 24th, 2008 • Category: Biology      Get in Amazon

Mitochondria: Practical Protocols (Methods in Molecular Biology)


Mitochondria: Practical Protocols (Methods in Molecular Biology)
By Dario Leister, Johannes M. Herrmann


Publisher: Humana Press
Number Of Pages: 592
Publication Date: 2007-06-12
ISBN-10 / ASIN: 1588296679
ISBN-13 / EAN: 9781588296672
Binding: Hardcover

Mitochondrial Genomics and Proteomics Protocols offers a broad collection of methods for studying the molecular biology, function, and features of mitochondria. In the past decade, mitochondrial research has elucidated the important influence of mitochondrial processes on integral cell processes such as apoptosis and cellular aging. This practical guide presents a wide spectrum of mitochondrial methods, each written by specialists with solid experience and intended for implementation by novice and expert researchers alike.

Part I introduces major experimental model systems and discusses their specific advantages and limitations for functional analysis of mitochondria. The concise overview of general properties of mitochondrial systems is supplemented by detailed protocols for cultivation of model organisms. Parts II-VI comprise a robust collection of protocols for studying different molecular aspects of mitochondrial functions including: genetics and microbiology, biochemistry, physiology, dynamics and morphology, and functional genomics. Emphasis is placed on new and emerging topics in mitochondrial study, such as the examination of apoptotic effects, fusion and fission of mitochondria, and proteome and transcriptome analysis.

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