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Medicinal Natural Products: A Biosynthetic Approach 0471496405

By addebook • Jul 15th, 2008 • Category: Pharmacy      Get in Amazon

Medicinal Natural Products: A Biosynthetic Approach


Medicinal Natural Products: A Biosynthetic Approach
By Paul M. Dewick

Publisher: John Wiley & Sons
Number Of Pages: 520
Publication Date: 2001-12-15
ISBN-10 / ASIN: 0471496405
ISBN-13 / EAN: 9780471496403
Binding: Paperback

Medicinal Natural Products, Second Edition is a comprehensive guide providing information on all classes of natural products in medicine. It builds upon fundamental chemical principles and demonstrates a unique integration of plant, microbial and animal natural products in one volume. The text guides the reader through a wealth of diverse natural metabolites used in medicine with sources, production methods, use as drugs and modes of action all extensively covered. Taking a chemistry based approach it combines traditional pharmacognosy with medicinal chemistry. The structure is user-friendly and includes the acclaimed grey boxes on groups of products and detailed mechanistic explanations.

Adopts a novel biosynthetic theme rather than a traditional descriptive approach
Includes extensive further reading at the end of the chapter
Thoroughly revised and updated to incorporate comprehensive coverage of plant, microbial and animal products
Includes the latest developments in the field
New material on genetic manipulation of biosynthetic pathways and non-mevalonate pathway to terpanoids
User-friendly format including extensive use of chemical schemes with annotated mechanistic explanations

Summary: A solid natural products text
Rating: 5

Medicinal Natural Products: A Biosynthetic Approach is an excellent text for the subject of natural products. There are a number of other text available but many (especially the older text) are really biochemical text disguised as natural products text (such as focusing on fatty acid biosynthesis rather than polyketide synthesis). In addition, many text are too short (I possess a text that describes biosynthetic reactions in 29 pages, a far too brief discussion of this complex field). This book is available in softcover at reasonable cost (a very desirable characteristic for students). I particularly enjoy the historical and pharmacological discussions of famous natural products. It is a good text for 1st year graduate students.

Summary: Very informative but needs more figures
Rating: 4

I enjoy reading this book, but I wish there were more mechanisms for the more ivovlved reactions. But, the book takes its time to review concepts and ensure understanding.

Summary: A Treasure
Rating: 5

This is really a wonderful book. The author has a deep insight in world of biosynthesis and medicinal natural products. I have read it all and am using it as a text to my undergaduate pharmacy students. It is just what i was looking for. Thanks Dr. Dewick, i am looking forward to see your second edition soon of this book, maybe this time we will have more about biosynthesis techniques!

Summary: A MUST for anybody interested in natural products chemistry!
Rating: 5

This text is absolutely superb and the only regret I have is that I did not write it myself! I have used it almost exclusively for the natural products chemistry component of our Bachelor of Pharmacy degree course and it comprehensively covers all of the major types of bioactive natural products. Anyone interested in Pharmacognosy will find the book an invaluable reference text. This book will be of great importance for future students of natural products chemistry. I thoroughly recommend its purchase!

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