Information Theory, Evolution, and The Origin of Life
By addebook • Jun 22nd, 2008 • Category: Biology •
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Information Theory, Evolution, and The Origin of Life
Publisher: Cambridge University Press
Number Of Pages: 272
Publication Date: 2005-04-18
Sales Rank: 525685
ISBN / ASIN: 0521802938
EAN: 9780521802932
Binding: Hardcover
Manufacturer: Cambridge University Press
Studio: Cambridge University Press
Average Rating: 4.5
Information Theory, Evolution and the Origin of Life presents a timely introduction to the use of information theory and coding theory in molecular biology. The genetical information system, because it is linear and digital, resembles the algorithmic language of computers. George Gamow pointed out that the application of Shannon’s information theory breaks genetics and molecular biology out of the descriptive mode into the quantitative mode and Dr Yockey develops this theme, discussing how information theory and coding theory can be applied to molecular biology. He discusses how these tools for measuring the information in the sequences of the genome and the proteome are essential for our complete understanding of the nature and origin of life. The author writes for the computer competent reader who is interested in evolution and the origins of life.
Review:
Dr. Yockey Scores Again!
This book, which is the long awaited follow-up to Information Theory and Molecular Biology, is another tour de force in a long history of such insights from Dr. Yockey. As the former head of the U.S. Government’s Aberdeen Proving Grounds, Yockey has a demonstrated history of squashing austensibly scientific ideas that superficially make sense, but when given the acid test are found entirely wanting. This book is replete with such deconstructions and they are much needed as they pertain to the current origin of life debate. Let me cite a few examples:
Perhaps formost among them is the idea that life arose from some Urschleim (primeval slime). Not only does Yockey show that this theory cannot be true, he explains exactly why, using mathematical certainty. First, he shows, applying Information theory to Crick’s Central Dogma, that because the flow of information can only pass from larger encoding alphabets to smaller ones, but not the other way around, it is impossible for the information which fills the genetic code to have proceded from proteins (the smaller alphabet) to DNA/RNA (the larger alphabet). Ergo, it is equally impossible for any proteins-first theory of life origin to be correct - simply on that basis. Because what matters is not so much the DNA itself, in the scheme of life’s continued existence, but the information it contains!
Next, he offers what may be the best summation of evidence in print to show that there simply is no scientific basis whatsoever to conclude that anything like Darwin’s “warm little pond” ever existed. But he goes much further, taking evidence from fossil records as to the nature of the earth’s atmosphere during the time the Urschleim was presumed to exist, Yockey shows that it is simply not possible chemically for earth to have had the atmosphere that it did and for those ponds to exist. The upshot being, according to cellular biologist and Nobel Laureate Christian Du Duve, without those ponds, the chance of any natural origin of life is zero.
Another strength of the book is the facility with which he ties the procedural activities of the genome to information theory, specifically Shannon’s Law. The importance here is his insight into the nature of codes. He begins by demonstrating that the genetic code, in its present optimal form, could not have had a natural origin simply because not enough time has existed since the beginning of the universe to allow for it’s actuality strictly in terms of processing.
He furthers this with the following quote from one of his earlier works: “The calculations presented in this paper show that the origin of a rather accurate genetic code, not necessarily the modern one, is a pons asinorum that must be crossed to pass over the abyss that separates crystallography, high polymer chemistry and physics from biology.(Yockey, 1981, 1992)” Then quoting from the book directly thereafter, “The paradox is seldom mentioned that enzymes are required to define or generate the reaction network, and the network is required to synthesize the enzymes and their component amino acids. There is no trace in physics or chemistry of the control of chemical reactions by a sequence of any sort or of a code between sequences. Thus, when we make the distinction between the origin of the genetic code and its evolution, we find the origin of the genetic code is unknowable.”
However, Yockey is not arguing for some kind of theistic event. In fact, he takes great pains later in the book to demonstrate that he does not support any theistic conclusion. From his perspective, while it is provably true, based on mathematical certainty, that the genetic code did not have a natural origin, because the universe has demonstrated no ability whatsoever to formulate any kind of code, let alone something as sophisticated as the genome, it cannot be assumed ipso facto that a supernatural event is the only other choice. Because there is no scientific evidence to support that possibility, Yockey is completely unwilling to postulate such, even in off-the-record conversations.
To further distance himself from any hint that he supports Intelligent Design (ID) with is work, he takes-on one of the icons of ID, Dr. Michael Behe, and his theory of Irreducible complexity (IR). The way in which he attempts to show that Behe’s theory does not work is to formulate IR as a kind of Gordian Knot that, if Behe is correct, is not computable. Because he can show that Behe’s model is computable, he believes he has shown Behe’s theory to be incorrect in principle.
However, his complete misunderstanding of Behe’s theory leads him to disprove something Behe did not theorize. Behe’s IR does not refer to a mathematically unsolvable puzzle, but to a kind of engineering dilemma for which there is no functional step-wise construction. Mechanisms for which there is no gradual, step by step approach to their completion, where every single step is itself a working model, are termed Irreducibly Complex. In other words, IR refers to any mechanism wherein all the parts necessary for its function are similtaneously extant because no partial iteration of the mechanism will function in any way.
I would use the example of a car engine. There is a net of engine parts required for the engine to run. Below that net assembly of parts, the engine will neither start nor run, even in principle. So while an engine is constructed sequentially, none of those sequences, short of a complete engine, will function, as is required by Darwinian gradualism.
Behe uses a simpler example, the mouse trap. His theory states that if you remove any one of the simple parts, it is impossible for the trap to function. The net result of Behe’s theory is that IR makes it impossible for any mechanism so possessed to evolve in a gradual way because all the parts have to be there at the start for the mechanism to work. On the other hand, Darwinian Gradualism requires that every step be not only an advancement in function, but a competitive advantage that allows the creature superior ability in the war for continued existence.
Though Yockey confuses Behe’s theory with the mathematical version of irreducibly complexity, to his credit, as the aforementioned quote from his book, regarding the impossibility of a network creating enzymes when enzymes themselves must first exist to make the network creating enzymes work [a classic Catch 22], he recognizes the irreducibly complex problem to which Behe refers. As such, while he discusses the it in completely different terms, his own example recognizes, as Behe theorizes, that it is impossible for such mechanisms to come into existence by some natural means.
That little flap is however, of no consequence in the panarama of Yockey’s book. Everything he has written on the subject of this book has become a must read for anyone who wants to be completely up to speed on the origin of life question. His original insights are powerful precisely because he goes beyond supposition and hypotheses cum theories, to show with the certainty of mathematical law, why some things cannot be. As a consequence, whenever amathematical biologists finally decide to stop arguing about matters that have already been definitively determined, and consult the wisdom and insights of one of a physicist who is one of the 20th century’s great scientific minds, they will devour this book.
John Tomlinson, MA, CHt
http://rapidshare.com/files/43831716/yoc0521802938.rar
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