Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases

By addebook • Jun 26th, 2008 • Category: Biology •

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Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases (Research and Perspectives in Alzheimer’s Disease)

Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases (Research and Perspectives in Alzheimer’s Disease)
By J. Cummings, J. Hardy, M. Poncet, Yves Christen

Publisher: Springer
Number Of Pages: 166
Publication Date: 2005-05-31
ISBN-10 / ASIN: 3540248358
ISBN-13 / EAN: 9783540248354
Binding: Hardcover

Recent advances in understanding the role of protein dysmetabolism in neurodegeneration was the theme of the Fondation IPSEN meeting addressing Genotype-Proteotype-Phenotype relationships. Experts from international laboratories contributed to the current volume to produce a comprehensive overview of the role of protein misfolding in neurodegeneration. Links between genotype and protein characteristics and between proteotype and clinical phenomenology were discussed across diseases categories. Progress in understanding the role of abnormalities of protein metabolism may lead to the identification of biological markers relevant to disease monitoring and to the development of new therapeutic agents capable of modifying and ameliorating basic neurodegenerative mechanisms.

Summary: Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases
Rating: 5

This is an up-to-date review of research in the area of genetics and clinical phenotypes in neurodegenerative diseases, particularly, in ALzheimer’s disease. the book provides the newest information and insights into the disease heredity and mechanism and proposes search for new treatments. Very enlightening!

Free download Links

http://rapidshare.com/files/124292257/GenProtPhenot.pdf