Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals
By addebook • Oct 1st, 2008 • Category: Medicine
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals
By Marc E. De Broe, George A. Porter, William M. Bennett, Gilbert Deray
Publisher: Springer
Number Of Pages: 1008
Publication Date: 2008-09-26
ISBN-10 / ASIN: 0387848428
ISBN-13 / EAN: 9780387848426
Binding: Hardcover
Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals, Third Edition is a comprehensive text on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The importance of the toxicity of drugs and other substances for the kidneys is increasingly recognized. The book consists of themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. In addition, the volume highlights specific types of drugs, such as anti-infectious agents and anti-inflammatory, cardiovascular and anti-cancer drugs. The last section deals with prevention and focuses on urinary biomarkers, pharmacological aspects and drug dosage in renal failure. In this third and completely revised edition, several new topics were added and additional figures and tables will be included.
The book is of interest for the nephrologist, internist, general practitioner, toxicologist, pharmacologist, anesthesiologist, epidemiologist, public health official, pharmaceutical industry, and national drug safety committees, among others.
Summary: Excepts from review by Bhavin Patel, PharmD
Rating: 5
DRUG-INDUCED nephropathy is of great interest given the
ever-growing number of medications, including herbal, that patients are taking. Also, it has become apparent that there are several environmental and industrial toxins thatcan cause nephropathy. Clinical Nephrotoxins: Renal Injury From Drugs and Chemicals is a hardcover book that explores the mechanisms by which medications, environmental toxins, and industrial
toxins can cause renal disease. The book is a 712-page, 35-chapter work, written by 95 international authors.
Most chapters have contributions from multiple authors and provide very good, up-to-date information and a very thorough reference list. Most of the chapters flow very well, often commenting (when applicable) on clinical manifestations, pathology, pathophysiology of renal injury (known or suspected),
and preventive measures. However, I will say that a couple of chapters did not follow this form, and I was slightly disappointed with these chapters. All chapters have figures and tables, including pictures of biopsies, when applicable. I found the figures and tables to be quite helpful and aided in my understanding of the topic being presented.
Overall, this book provides a very good overview on the mechanisms of drug- and toxin induced nephropathy.Up-to-date information on current clinically relevant medications (including herbal) and worldwide environmental and industrial toxins is provided. It would be a welcome addition to any health care provider’s collection of reference books.
Bhavin Patel, PharmD
Nephrology Clinical Pharmacy Specialist
Hennepin County Medical Center
Minneapolis, Minnesota
American Journal of Kidney Diseases, Vol 42, No 6 (December), 2003: p 1324 1324
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Thank you for the most useful textbook