Advances in Medicinal Chemistry, Volume 5 (Advances in Medicinal Chemistry)
By addebook • Aug 31st, 2008 • Category: Pharmacy •
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Advances in Medicinal Chemistry, Volume 5 (Advances in Medicinal Chemistry)
Advances in Medicinal Chemistry, Volume 5 (Advances in Medicinal Chemistry)
By A.B. Reitz, S.L. Dax
Publisher: Elsevier Science
Number Of Pages: 212
Publication Date: 2000-01-01
ISBN-10 / ASIN: 0762305932
ISBN-13 / EAN: 9780762305933
Binding: Hardcover
Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.
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